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PTPN11-Related Noonan Syndrome Predisposes to Multifocal Low-Grade CNS Tumors Harboring FGFR1 Variants

2026-01-28

Abstract excerpt

<title>Abstract</title> <p> <bold>Purpose:</bold> To characterize the clinical, radiological, and molecular characteristics of CNS tumors associated with Noonan syndrome (NS) and other non-Neurofibromatosis type 1 RASopathies. <bold>Methods:</bold> Twenty-four patients with concern for NS underwent clinical and central radiological review in this multi-institutional study. Whole-exome sequencing, RNA sequenci...

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Literature Corpus work
a61f1b42-dcce-5250-85d7-8870a0150d58
DOI
10.21203/rs.3.rs-8662616/v1
Open publication

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PTPN11-Related Noonan Syndrome Predisposes to Multifocal Low-Grade CNS Tumors Harboring FGFR1 VariantsDOI 10.21203/rs.3.rs-8662616/v1
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