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Diffuse leptomeningeal glioneuronal tumour (DLGNT) in children: the emerging role of genomic analysis

7 Sept 2021

Abstract excerpt

Diffuse leptomeningeal glioneuronal tumours (DLGNT) represent rare enigmatic CNS tumours of childhood. Most patients with this disease share common radiological and histopathological features but the clinical course of this disease is variable. A radiological hallmark of this disease is widespread leptomeningeal enhancement that may involve the entire neuroaxis with predilection for the posterior fossa and spine....

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PMID: 34493325
DOI: 10.1186/s40478-021-01248-w

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