Article

The Mechanism underlying B cell Developmental Dysfunction in Kawasaki Disease Based on Single-cell Transcriptomic Sequencing

2023-02-21

Abstract excerpt

<h4>Background</h4> Kawasaki disease (KD) is an acute systemic vasculitis that can lead to acquired heart disease in children mostly from in developed countries. The previous research showed that B cells in KD patients underwent a profound change in both the cell numbers and types after intravenous immunoglobulin (IVIG) therapy. <h4>Methods</h4> We performed the single-cell RNA-sequencing for the peripheral bloo...

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Literature Corpus work: a6198b9b-d419-527a-8dae-68c75faec064
DOI: 10.1101/2023.02.21.529340

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