Article

Single-cell Landscape of T Cell Heterogeneity in Kawasaki Disease: STAT3/JAK Axis Regulates the Lineage Differentiation Bias of Th17 Cells

2026-03-23

Abstract excerpt

<h4>Background</h4> Kawasaki disease (KD) is a pediatric systemic vasculitis in which T-cell-mediated immune responses play a pivotal role. However, the precise dynamic evolution of T-cell subsets during disease progression remains poorly understood. <h4>Methods</h4> Single-cell RNA sequencing (scRNA-seq) was employed to perform high-resolution annotation of peripheral blood mononuclear cells (PBMCs) from health...

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Literature Corpus work: 07399ac2-1d3f-56a0-889d-8acfb66a7765
DOI: 10.64898/2026.03.18.712795

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