Article

Delineation of Single-cell Altas Provides New Insights for Development of Coronary Artery Lesions in Kawasaki Disease: Bad and Good Signaling Molecules

2024-11-15

Abstract excerpt

<h4>Background</h4> Kawasaki Disease (KD) is a vasculitis syndrome featured with a high and persistent fever and mainly affects children under 5 years of age. It is the leading cause of acquired heart disease in the form of coronary artery lesions (CALs) for children in developed countries. Most KD can be relieved with the high-dosage Intravenous immunoglobulin (IVIG) therapy, but a small proportion develop CALs...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 418f2ea2-d14b-53c4-804c-03b9956d8e97
DOI: 10.1101/2024.11.13.623351

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Delineation of Single-cell Altas Provides New Insights for Development of Coronary Artery Lesions in Kawasaki Disease: Bad and Good Signaling MoleculesDOI 10.1101/2024.11.13.623351Read

The Mechanism underlying B cell Developmental Dysfunction in Kawasaki Disease Based on Single-cell Transcriptomic SequencingSemantic proximity Read

CD14+ monocytes: the immune communication hub in early vasculitis symptoms of Kawasaki diseaseSemantic proximity Read

Single-cell RNA-seq reveals altered plasma cell subsets and decreased cytotoxicity of NK cells in patients with Kawasaki diseaseSemantic proximity Read

Utilizing Single-cell RNA Sequencing for Analyzing the Characteristics of PBMC in Patients with Kawasaki DiseaseSemantic proximity Read

Utilizing single-cell RNA sequencing for analyzing the characteristics of PBMC in patients with Kawasaki diseaseSemantic proximity Read

Genome-wide transcriptome analysis to further understand neutrophil activation and lncRNA transcript profiles in Kawasaki diseaseSemantic proximity Read

Aberrant peripheral immune responses in acute Kawasaki disease with single-cell sequencingSemantic proximity Read

Integration of scRNA-Seq and bulk RNA-Seq uncover perturbed immune cell types and pathways of Kawasaki diseaseSemantic proximity Read

Single-cell RNA sequencing of peripheral blood mononuclear cells from acute Kawasaki disease patientsSemantic proximity Read

The transcriptional profile of coronary arteritis in Kawasaki diseaseSemantic proximity Read

Single cell RNA-seq resolution revealed CCR1+/SELL+/XAF+ CD14 monocytes mediated vascular endothelial cell injuries in Kawasaki disease and COVID-19Semantic proximity Read

Expression Profile Analysis of Differentially Expressed Genes in Human Coronary Artery Endothelial Cells Induced by Serum From Kawasaki Disease: A Preliminary StudySemantic proximity Read