Article

Dissecting CD8+ T cell pathology of severe SARS-CoV-2 infection by single-cell epitope mapping

2021-03-03

Abstract excerpt

The current COVID-19 pandemic represents a global challenge. A better understanding of the immune response against SARS-CoV-2 is key to unveil the differences in disease severity and to develop future vaccines targeting novel SARS-CoV-2 variants. Feature barcode technology combined with CITE-seq antibodies and DNA-barcoded peptide-MHC I Dextramer reagents enabled us to identify relevant SARS-CoV-2-derived epitopes...

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Literature Corpus work: a5b8f805-03d6-5140-9811-772b58106c4d
DOI: 10.1101/2021.03.03.432690

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