Article

The IgG3 Subclass of β1-adrenergic receptor autoantibody is an endogenous biaser of β1AR signaling

2020-09-18

Abstract excerpt

<h4>ABSTRACT</h4> Autoantibodies recognizing human β1ARs generated due to dysregulation in autoimmune response are generally associated with deleterious cardiac outcomes. However, cellular studies show that isolates of β1AR autoantibody from patients differentially modulate β1AR function. β1AR autoantibodies belong to the IgG class of immunoglobulins, however it is not known whether the IgG sub-classes mediate va...

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Literature Corpus work: a5ad17b6-76fa-5c79-94e5-7f6982083aaa
DOI: 10.1101/2020.09.17.302059

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