Article

Detecting tumor-associated peptides from the plasma-derived soluble immunopeptidome in human hepatocellular carcinoma patients: a pilot study

2026-07-07

Abstract excerpt

<title>Abstract</title> <p>Background and aims. Hepatocellular carcinoma (HCC) shows limited response to checkpoint inhibitor therapy, leaving opportunities for antigen-based immunotherapy and improved disease monitoring. This study evaluates the plasma-derived soluble HLA-I (sHLA-I) peptidome as a minimally invasive source of tumor-associated antigens (TAAs) for personalized treatment and diagnostics in HCC. Met...

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Literature Corpus work: 6534c43f-0e44-5058-81b9-0aea45283f7e
DOI: 10.21203/rs.3.rs-9929854/v1

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