Article

The Effects of Hif-1 Gene on the Expression of IL-10, TGF-β and Versican Genes in Human Bone Marrow and Adipose Tissue Mesenchymal Stem

2022-02-09

Abstract excerpt

Mesenchymal stem cells (MSCs) derived from bone marrow and adipose tissues are often hypoxic. These cells are important in tissue repair as well as in the secretion of anti-inflammatory factors and reduction of inflammation. IL-10 and TGF-β are anti-inflammatory cytokines and play an important role in the immune system by modulating inflammation. Versican is a protein that plays an important role in repairing dama...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a575494a-8abc-5703-9bc3-40ed6b868f56
DOI: 10.21203/rs.3.rs-1222431/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The Effects of Hif-1 Gene on the Expression of IL-10, TGF-β and Versican Genes in Human Bone Marrow and Adipose Tissue Mesenchymal StemDOI 10.21203/rs.3.rs-1222431/v1Read

TGF-β2 is involved in the preservation of the chondrocyte phenotype under hypoxic conditions.Semantic proximity Read

Hypoxia Inducible Factor-1α in Pulmonary Fibrosis: A Promising Therapeutic TargetSemantic proximity Read

Effect of Hypoxia on Gene Expression of Bone Marrow-Derived Mesenchymal Stem Cells and Mononuclear CellsSemantic proximity Read

Hypoxia Preconditioning of Human MSCs: a Direct Evidence of HIF-1α and Collagen Type XV CorrelationSemantic proximity Read

Hypoxic Preconditioning Promotes Survivals of Human Adipocyte Mesenchymal Stem Cell via Expression of Prosurvival and Proangiogenic BiomarkersSemantic proximity Read

Hypoxic mast cells accelerate the proliferation, collagen accumulation and phenotypic alteration of human lung fibroblasts.Semantic proximity Read

Therapeutic effects of Hypoxia-Inducible Factor-1α (HIF-1α) on bone formation around implants in diabetic miceSemantic proximity Read

Hypoxic Preconditioning Promotes Survival of Human Adipose Derived Mesenchymal Stem CellSemantic proximity Read

Hypoxia promotes osteogenesis but suppresses adipogenesis of human mesenchymal stromal cells in a hypoxia-inducible factor-1 dependent manner.Semantic proximity Read

Marrow-Derived Stromal Cells Express Genes Encoding a Broad Spectrum of Arteriogenic Cytokines and Promote In Vitro and In Vivo Arteriogenesis Through Paracrine MechanismsSemantic proximity Read

Microenvironmental Interaction Between Hypoxia and Endothelial Cells Controls the Migration Ability of Placenta‐Derived Mesenchymal Stem Cells via α4 Integrin and Rho SignalingSemantic proximity Read

Human Articular Chondrocytes Retain Their Phenotype in Sustained Hypoxia While Normoxia Promotes Their Immunomodulatory Potential.Semantic proximity Read