Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DYRK-family kinases regulate Candida albicans morphogenesis and virulence through the Ras1/PKA pathway

28 Nov 2023

Abstract excerpt

ABSTRACT Candida albicans is an opportunistic human fungal pathogen that causes common superficial mycoses in healthy populations and invasive disease in immunocompromised individuals. The fungus employs several virulence traits to cause disease in humans, including its ability to transition from yeast to filamentous morphologies. Previous work found that genetic or pharmacological inhibition of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antifungal resistance and susceptibility
Share to Fungal and yeast genetics research
Share to Fungal Infections and Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38015416
DOI: 10.1128/mbio.02183-23

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DYRK-family kinases regulate Candida albicans morphogenesis and virulence through the Ras1/PKA pathwayPMID 38015416Read ↗

<i>Candida albicans</i> filamentation does not require the cAMP-PKA pathway in vivoSemantic proximity Read ↗

Signaling through Lrg1, Rho1 and Pkc1 Governs Candida albicans Morphogenesis in Response to Diverse CuesSemantic proximity Read ↗

Systematic analysis of the Candida albicans kinome reveals environmentally contingent protein kinase-mediated regulation of filamentation and biofilm formation in vitro and in vivoSemantic proximity Read ↗

The Yak1 kinase is involved in the initiation and maintenance of hyphal growth in Candida albicans.Semantic proximity Read ↗

Adenylyl Cyclase and Protein Kinase A Play Redundant and Distinct Roles in Growth, Differentiation, Antifungal Drug Resistance, and Pathogenicity of Candida auris.Semantic proximity Read ↗

Protein kinase A governs growth and virulence in Candida tropicalisSemantic proximity Read ↗

Deciphering the regulatory mechanisms of the cAMP/protein kinase A pathway and their roles in the pathogenicity of Candida aurisSemantic proximity Read ↗

Ras Signaling Gets Fine-Tuned: Regulation of Multiple Pathogenic Traits of Candida albicansSemantic proximity Read ↗

Multiple roles and diverse regulation of the Ras/cAMP/protein kinase A pathway in Candida albicansSemantic proximity Read ↗

The Ras/cAMP/PKA signaling pathway and virulence in <i>Candida albicans</i>Semantic proximity Read ↗

Signaling pathways governing the pathobiological features and antifungal drug resistance of Candida aurisSemantic proximity Read ↗

Global regulatory roles of the cAMP/PKA pathway revealed by phenotypic, transcriptomic and phosphoproteomic analyses in a null mutant of the PKA catalytic subunit in Candida albicans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.