Article

Psychosis spectrum symptoms among individuals with schizophrenia-associated copy number variants and evidence of cerebellar correlates of symptom severity

2022-03-05

Abstract excerpt

The 3q29 deletion (3q29Del) is a copy number variant (CNV) with one of the highest effect sizes for psychosis- risk (>40-fold). Systematic research offers promising avenues for elucidating mechanism; however, compared to CNVs like 22q11.2Del, 3q29Del remains understudied. Emerging findings indicate that posterior fossa abnormalities are common among carriers, but their clinical relevance is unclear. Here, we repor...

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Literature Corpus work: a5247d9b-73c5-50e7-9408-a99d985d03d6
DOI: 10.1101/2022.03.03.22271848

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