Article

In-depth immunophenotyping with mass cytometry during TB treatment reveals non-canonical T-cell subsets associated with sputum culture conversion

2021-10-28

Abstract excerpt

Tuberculosis (TB) is a difficult-to-treat infection because of multidrug regimen requirements based on drug susceptibility profiles and treatment observance issues. TB cure is defined by mycobacterial sterilization, technically complex to systematically assess. We hypothesized that microbiological outcome was associated with stage-specific immune changes in peripheral whole blood during TB treatment. The T-cell ph...

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Literature Corpus work: a4fe7f5a-3b80-58af-95be-5148d8225b4c
DOI: 10.1101/2021.10.27.466125

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