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Article

Search for Specific Biomarkers of IFNβ Bioactivity in Patients with Multiple Sclerosis

23 Aug 2011

Abstract excerpt

Myxovirus A (MxA), a protein encoded by the MX1 gene with antiviral activity, has proven to be a sensitive measure of IFNβ bioactivity in multiple sclerosis (MS). However, the use of MxA as a biomarker of IFNβ bioactivity has been criticized for the lack of evidence of its role on disease pathogenesis and the clinical response to IFNβ. Here, we aimed to identify specific biomarkers of IFNβ bioactivity in order to...

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PMID: 21886806
DOI: 10.1371/journal.pone.0023634

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