Article

The Innate Immune Response to Ischemic Injury: a Multiscale Modeling Perspective

2018-01-17

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Cell death as a result of ischemic injury triggers powerful mechanisms regulated by germline-encoded Pattern Recognition Receptors (PRRs) with shared specificity that recognize invading pathogens and endogenous ligands released from dying cells, and as such are essential to human health. Alternatively, dysregulation of these mechanisms contributes to extreme inflammation, de...

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Literature Corpus work: a4e7b3d0-5c3e-512b-b2f8-9ac3bd970da7
DOI: 10.1101/249599

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