Article

Automated liquid handling extraction and rapid quantification of underivatized amino acids and tryptophan metabolites from human serum and plasma using dual-column U(H)PLC-MRM-MS and its application to prostate cancer study

2024-01-01

Abstract excerpt

Free amino acids (AAs) and their metabolites are important building blocks, energy sources and signaling molecules associated with various pathological phenotypes. The quantification of AA and tryptophan (TRP) metabolites in human serum and plasma is therefore of great diagnostic interest. Robust and reproducible sample extraction and processing workflows as well as rapid, sensitive absolute quantification of AA a...

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Literature Corpus work: a4d5fded-fc31-5300-b627-8bfe02c6c1ae
DOI: 10.1101/2023.12.31.573763

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