Article

DeCompress: tissue compartment deconvolution of targeted mRNA expression panels using compressed sensing

2020-08-14

Abstract excerpt

<h4>ABSTRACT</h4> Targeted mRNA expression panels, measuring up to 800 genes, are used in academic and clinical settings due to low cost and high sensitivity for archived samples. Most samples assayed on targeted panels originate from bulk tissue comprised of many cell types, and cell-type heterogeneity confounds biological signals. Reference-free methods are used when cell-type-specific expression references are...

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Literature Corpus work: a49b2594-3c28-5e61-9ded-b1061426684f
DOI: 10.1101/2020.08.14.250902

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