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Article

Lower promoter activity of the <i>ST8SIA2</i> gene has been favored in evolving human collective brains

2021-04-11

Abstract excerpt

ST8SIA2 is the main factor regulating expression of the phenotype involved in schizophrenia. Lowered promoter activity of the ST8SIA2 gene is considered to be protective against schizophrenia by conferring tolerance to psychosocial stress. Here, we examined the promoter type composition of anatomically modern humans (AMHs) and archaic humans (AHs; Neanderthals and Denisovans), and compared the promoter activity a...

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Literature Corpus work
a476d584-2c6a-560f-9719-4a707e946d04
DOI
10.1101/2021.04.11.439101
Open publication

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Lower promoter activity of the <i>ST8SIA2</i> gene has been favored in evolving human collective brainsDOI 10.1101/2021.04.11.439101
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