Article
Lower promoter activity of the <i>ST8SIA2</i> gene has been favored in evolving human collective brains
2021-04-11
Abstract excerpt
ST8SIA2 is the main factor regulating expression of the phenotype involved in schizophrenia. Lowered promoter activity of the ST8SIA2 gene is considered to be protective against schizophrenia by conferring tolerance to psychosocial stress. Here, we examined the promoter type composition of anatomically modern humans (AMHs) and archaic humans (AHs; Neanderthals and Denisovans), and compared the promoter activity a...
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Identifiers and source
- Literature Corpus work
- a476d584-2c6a-560f-9719-4a707e946d04
- DOI
- 10.1101/2021.04.11.439101
