Article

High IGKC Expressing Intratumoral Plasma Cells Predict Response to Immune Checkpoint Blockade

2022-07-05

Abstract excerpt

Resistance to Immune Checkpoint Blockade (ICB) constitutes the current limiting factor for the optimal implementation of this novel therapy that otherwise demonstrates durable responses with acceptable toxicity scores. This limitation is exacerbated by a lack of robust biomarkers. In this study, we have dissected the basal TME composition at the gene expression and cellular levels that predict response to Nivoluma...

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Identifiers and source

Literature Corpus work: a4688960-6980-5fe8-b18b-5860fd38124b
DOI: 10.20944/preprints202207.0072.v1

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