Article
CCR5 Decorated Rilpivirine Lipid Nanoparticles Build Myeloid Drug Depots Which Sustains Antiretroviral Activities
2024-06-03
Abstract excerpt
<title>Abstract</title> <p>Antiretroviral therapy (ART) improves the quality of life for those living with the human immunodeficiency virus type one (HIV-1). However, poor compliance reduces ART effectiveness and leads to immune compromise, viral mutations, and disease co-morbidities. A novel drug formulation is made whereby a lipid nanoparticle (LNP) carrying rilpivirine (RPV) is decorated with the C-C chemokine...
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Identifiers and source
- Literature Corpus work
- a43dbd03-b3ae-5732-a879-9065eec3d329
- DOI
- 10.21203/rs.3.rs-4433306/v1
