HIV Virion Capturing Liposomes for Therapeutic Vaccination

Abstract excerpt

HIV infection currently has no effective cures and requires lifelong antiretroviral treatments. Cures have failed due to HIV’s immune evasion and rapid mutation rate. Here we present a first in class HIV therapeutic vaccine, termed nanotrap therapeutic vaccines (NTVs) that are designed to capture circulating HIV virions and facilitate internalization by local antigen presenting cells. NTVs are modified liposomes t...

Topics

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• Animal Virus Infections Studies
• Bacteriophages and microbial interactions
• HIV Research and Treatment
• Immunotherapy and Immune Responses
• Monoclonal and Polyclonal Antibodies Research
• Respiratory viral infections research
• vaccines and immunoinformatics approaches
• Viral gastroenteritis research and epidemiology

Identifiers and source

Literature Corpus work

cefccc40-04c0-5063-99bd-928b8776f177

DOI

10.1101/2025.11.24.690259