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Article

Proteasomal ubiquitin receptor RPN-10 controls sex determination in Caenorhabditis elegans.

Molecular biology of the cell - 1 Dec 2006

Shimada Masumi, Kanematsu Kenji, Tanaka Keiji, Yokosawa Hideyoshi, Kawahara Hiroyuki

Abstract excerpt

The ubiquitin-binding RPN-10 protein serves as a ubiquitin receptor that delivers client proteins to the 26S proteasome. Although ubiquitin recognition is an essential step for proteasomal destruction, deletion of the rpn-10 gene in yeast does not influence viability, indicating redundancy of the substrate delivery pathway. However, their specificity and biological relevance in higher eukaryotes is still...

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Source

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Identifiers

PMID: 17050737
DOI: 10.1091/mbc.e06-05-0437
PMCID: PMC1687211

Genes

TRA

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Source receipt: pubmed, retrieved 7 Sept 2026.

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