Article
Caenorhabditis elegans p97 controls germline-specific sex determination by controlling the TRA-1 level in a CUL-2-dependent manner.
Journal of cell science - 15 Oct 2009
Sasagawa Yohei, Otani Mieko, Higashitani Nahoko, Higashitani Atsushi, Sato Ken, Ogura Teru, Yamanaka Kunitoshi
Abstract excerpt
p97 (CDC-48 in Caenorhabditis elegans) is a ubiquitin-selective AAA (ATPases associated with diverse cellular activities) chaperone and its key function is to disassemble protein complexes. p97 functions in diverse cellular processes including endoplasmic reticulum (ER)-associated degradation, membrane fusion, and meiotic and mitotic progression. However, its cellular functions in development have not yet been...
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