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A multicomponent intranasal adjuvant drives durable humoral, cellular, and mucosal immune responses to SARS-CoV-2 in young and aged mice.

2023-01-20

Abstract excerpt

<title>Abstract</title> <p>Multiple FDA-approved SARS-CoV-2 vaccines provide excellent protection against severe disease. Despite this, immunity can wane relatively fast, particularly in the elderly and novel viral variants capable of evading infection- and vaccination-induced immunity continue to emerge. Intranasal (IN) vaccination more effectively induces mucosal immune responses than parenteral vaccines, which...

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Literature Corpus work
d4ef459a-8f62-5380-ad7d-1e9c827cf18a
DOI
10.21203/rs.3.rs-2457013/v1
Open publication

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A multicomponent intranasal adjuvant drives durable humoral, cellular, and mucosal immune responses to SARS-CoV-2 in young and aged mice.DOI 10.21203/rs.3.rs-2457013/v1
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