Article
The Francisella pathogenicity island.
Annals of the New York Academy of Sciences - 1 Jun 2007
Nano Francis E, Schmerk Crystal
Abstract excerpt
The Francisella pathogenicity island (FPI) is a cluster of 16-19 genes, which is found duplicated in most of the Francisella genomes that have been sequenced. Although 16 FPI genes are highly conserved there are 2-3 putative genes that are absent or interrupted by stop codons in some strains. Francisella strains with experimentally induced mutations in FPI genes are highly attenuated in virulence and show defects...
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