Article
Type IV pili in Francisella tularensis: roles of pilF and pilT in fiber assembly, host cell adherence, and virulence.
Infection and immunity - 1 Jul 2008
Chakraborty Subhra, Monfett Michael, Maier Tamara M, Benach Jorge L, Frank Dara W, Thanassi David G
Abstract excerpt
Francisella tularensis, a highly virulent facultative intracellular bacterium, is the causative agent of tularemia. Genome sequencing of all F. tularensis subspecies revealed the presence of genes that could encode type IV pili (Tfp). The live vaccine strain (LVS) expresses surface fibers resembl...
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