Article

Platelet Thrombus Formation in eHUS is Prevented by Anti-MBL2

2019-07-18

Abstract excerpt

Epidemic Hemolytic Uremic Syndrome (eHUS) caused by Shiga toxin-producing bacteria is characterized by thrombocytopenia, microangiopathic hemolytic anemia, and acute kidney injury that cause acute renal failure in up to 65% of affected patients. We hypothesized that the mannose-binding lectin (MBL) pathway of complement activation plays an important role in human eHUS, as we previously demonstrated that injection...

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Literature Corpus work: a3c76886-92cc-5314-8d8d-9745ff88bb0a
DOI: 10.1101/707364

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