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Article

Pathogenesis and prognosis of thrombotic microangiopathy.

Clinical and experimental nephrology - 1 Jun 2007

Nangaku Masaomi, Nishi Hiroshi, Fujita Toshiro

Abstract excerpt

Thrombotic microangiopathy (TMA) is a clinicopathological syndrome characterized by thrombosis formation in the microvasculature of various organs. Included in the broad category of TMA are the hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP). Typical HUS is caused by Escherichia coli O157:H7, which produces the Shiga-like toxins; Stx-1 and Stx-2. In addition to damaging endothelial...

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Source

Identifiers

PMID: 17593509
DOI: 10.1007/s10157-007-0466-7

Genes

ADAMTS13

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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