Article

A harmonized single-cell RNA-seq atlas of human localized and metastatic prostate cancers and benign tissues

2026-05-20

Abstract excerpt

Single-cell RNA sequencing (scRNA-seq) effectively captures the differences in transcriptomic landscape of cell types and cell states between benign and cancer tissues. Pooling publicly available datasets distributed across independent studies enables increased sample representation and cross-study comparisons. Here we present a harmonized scRNA-seq atlas of the human prostate constructed by integrating 17 availab...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a328b6f8-72ae-5cc2-9460-eb56ff8ba8c0
DOI: 10.64898/2026.05.18.725966

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A harmonized single-cell RNA-seq atlas of human localized and metastatic prostate cancers and benign tissuesDOI 10.64898/2026.05.18.725966Read

Integrated analysis of single-cell and bulk transcriptomes uncovers clinically relevant molecular subtypes in human prostate cancerSemantic proximity Read

Single-Cell and Spatial Transcriptomic Profiling Reveals Epithelial Functional States and Fibroblast Phenotypes in Hormone Therapy-Naïve Localized Prostate Cancer.Semantic proximity Read

Unveiling novel double-negative prostate cancer subtypes through single-cell RNA sequencing analysisSemantic proximity Read

Integrated single-cell and spatial transcriptomic analyses unravel the heterogeneity of the prostate tumor microenvironmentSemantic proximity Read

Application and new findings of scRNA-seq and ST-seq in prostate cancerSemantic proximity Read

Deciphering single-cell heterogeneity and cellular ecosystem dynamics during prostate cancer progressionSemantic proximity Read

Single-Cell Proteomics Defines the Cellular Heterogeneity of Localized Prostate CancerSemantic proximity Read

Unveiling Novel Double-Negative Prostate Cancer Subtypes Through Single-Cell RNA Sequencing AnalysisSemantic proximity Read

Single-cell proteomics defines the cellular heterogeneity of localized prostate cancerSemantic proximity Read

Integrated single-cell and spatial transcriptomic analyses unravel the heterogeneity of the prostate tumor microenvironmentSemantic proximity Read

Coordinating single‐cell and bulk RNA ‐seq in deciphering the intratumoral immune landscape and prognostic stratification of prostate cancer patientsSemantic proximity Read

The implications of single-cell RNA-seq analysis in prostate cancer: unraveling tumor heterogeneity, therapeutic implications and pathways towards personalized therapySemantic proximity Read