Article

Polymyxin B Hemoadsorption efficiently removes Gram-Negative-derived Quorum Sensing molecules responsible for acute kidney tubular epithelial cell injury

2025-02-19

Abstract excerpt

<title>Abstract</title> <p><bold>Background.</bold> Lipopolysaccharide (LPS) is the main driver of sepsis-associated Acute Kidney Injury (SA-AKI) in Gram-Negative infections and its removal by Polymyxin-B Hemoadsorption (PMX-HA) has been evaluated in clinical trials. Quorum Sensing (QS), diffusible signal molecules used by Gram-Positive and Gram-Negative bacteria for intercellular communication, can interact with...

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Literature Corpus work: a30e1629-994f-5e14-ab47-72a0556cc17a
DOI: 10.21203/rs.3.rs-6032315/v1

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Polymyxin B Hemoadsorption efficiently removes Gram-Negative-derived Quorum Sensing molecules responsible for acute kidney tubular epithelial cell injuryDOI 10.21203/rs.3.rs-6032315/v1Read

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