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Challenges and Limitations of Anti-quorum Sensing Therapies

31 Oct 2019

Abstract excerpt

Quorum sensing (QS) is a mechanism allowing microorganisms to sense population density and synchronously control genes expression. It has been shown that QS supervises the activity of many processes important for microbial pathogenicity, e.g., sporulation, biofilm formation, and secretion of enzymes or membrane vesicles. This contributed to the concept of anti-QS therapy [also called quorum quenching (QQ)] and...

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PMID: 31736912
DOI: 10.3389/fmicb.2019.02473

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