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Article

Paradigms of acute kidney injury in the intensive care setting.

Nature reviews. Nephrology - 1 Apr 2018

Kellum John A, Prowle John R

Abstract excerpt

Acute kidney injury (AKI) is a heterogeneous clinical syndrome that has multiple aetiologies, variable pathogenesis and diverse outcomes. However, these heterogeneities are not reflected in current approaches to the diagnosis and, to some degree, treatment of AKI. For example, congestive heart failure and dehydration can produce identical changes in serum creatinine level and urine output (parameters that are...

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Acute Kidney Injury
Biomarkers
Intensive Care Units
Phenotype
Prognosis

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PMID: 29355173
DOI: 10.1038/nrneph.2017.184

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