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NF-κB in Hematological Malignancies

31 May 2017

Abstract excerpt

NF-κB (Nuclear Factor Κ-light-chain-enhancer of activated B cells) transcription factors are critical regulators of immunity, stress response, apoptosis, and differentiation. Molecular defects promoting the constitutive activation of canonical and non-canonical NF-κB signaling pathways contribute to many diseases, including cancer, diabetes, chronic inflammation, and autoimmunity. In the present review, we focus...

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PMID: 28561798
DOI: 10.3390/biomedicines5020027

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