Article
Lysophosphatidylcholine induces heat pain hypersensitivity in obese mice fed with a high-fat diet through activation of peripheral Acid-Sensing Ion Channel 3
2021-12-09
Abstract excerpt
Diet induced obesity is one of the major causes of obesity, which affects 13% of the world’s adult population. Obesity is correlated to chronic pain regardless of other components of the metabolic syndrome. Our study focuses on investigating the effect of high-fat diet induced obesity on peripheral sensory neurons activity and pain perception, followed by deciphering the underlying cellular and molecular mechanism...
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Identifiers and source
- Literature Corpus work
- a2f9c6c6-cbdf-5829-a12b-4b2c7b657685
- DOI
- 10.1101/2021.12.07.471593
