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Article

Role of Janus Kinase 3 in Predisposition to Obesity-associated Metabolic Syndrome.

The Journal of biological chemistry - 4 Dec 2015

Mishra Jayshree, Verma Raj K, Alpini Gianfranco, Meng Fanyin, Kumar Narendra

Abstract excerpt

Obesity, a worldwide epidemic, is a major risk factor for the development of metabolic syndrome (MetS) including diabetes and associated health complications. Recent studies indicate that chronic low-grade inflammation (CLGI) plays a key role in metabolic deterioration in the obese population. Previously, we reported that Jak3 was essential for mucosal differentiation and enhanced colonic barrier functions and...

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Identifiers

PMID: 26451047
DOI: 10.1074/jbc.M115.670331
PMCID: PMC4705936

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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