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Alterations in the preneoplastic breast microenvironment of <i>BRCA1/2</i> mutation carriers revealed by spatial transcriptomics

2023-05-25

Abstract excerpt

Breast cancer is the most common cancer in females, affecting one in every eight women and accounting for the majority of cancer-related deaths in women worldwide. Germline mutations in the BRCA1 and BRCA2 genes are significant risk factors for specific subtypes of breast cancer. BRCA1 mutations are associated with basal-like breast cancers, whereas BRCA2 mutations are associated with luminal-like disease. The...

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Literature Corpus work
a2d53dfc-ed50-56b4-809a-fd86a093f7c1
DOI
10.1101/2023.05.24.542078
Open publication

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Alterations in the preneoplastic breast microenvironment of <i>BRCA1/2</i> mutation carriers revealed by spatial transcriptomicsDOI 10.1101/2023.05.24.542078
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