Article
Lipid levels correlate with neuronal and dopaminergic markers during the differentiation of SH-SY5Y cells
2023-09-02
Abstract excerpt
Parkinson’s Disease (PD) is characterized by the loss of dopaminergic neurons and the deposition in the remaining cells of protein inclusions called Lewy Bodies (LBs). LBs are heterogeneous structures composed of protein and lipid molecules and their main constituent is the presynaptic protein α-synuclein. SH-SY5Y cells are neuroblastoma cells commonly used to model PD because they express dopaminergic markers and...
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Identifiers and source
- Literature Corpus work
- a2a19cc3-5857-57d3-a43f-2aae8f688477
- DOI
- 10.1101/2023.09.01.555964
