Article

Expanded detection and impact of <i>BAP1</i> alterations in cancer

2023-11-21

Abstract excerpt

Aberrant expression of the BAP1 tumor suppressor gene is a prominent risk factor for several tumor types and is important in tumor evolution and progression. Here we performed integrated multi-omic analyses using data from The Cancer Genome Atlas (TCGA) for 33 cancer types and over 10,000 individuals to identify alterations leading to BAP1 disruption. We combined existing variant calls and new calls derived from...

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Literature Corpus work: 815ba56d-27d2-5c36-963d-8510da8033fa
DOI: 10.1101/2023.11.21.568094

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