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Single Cell Spatial Transcriptomics of the Murine Embryonic Palate Links Pax9 to Patterning and Organization of Extracellular Matrix Components

2025-02-19

Abstract excerpt

<title>Abstract</title> <p>Despite advances in understanding the morphological disruptions that lead to defects in palate formation, the precise perturbations within the signaling microenvironment of palatal clefts remain poorly understood. To explore in greater depth the genomic basis of palatal clefts, we designed and implemented the first single cell spatial RNA-sequencing study in a cleft palate model, utiliz...

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Literature Corpus work
03ef1b55-de6e-5e10-bfc9-c7166881071b
DOI
10.21203/rs.3.rs-5969552/v1
Open publication

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Single Cell Spatial Transcriptomics of the Murine Embryonic Palate Links Pax9 to Patterning and Organization of Extracellular Matrix ComponentsDOI 10.21203/rs.3.rs-5969552/v1
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