Article

Tumor control via targeting PD-L1 with chimeric antigen receptor modified NK cells

2020-01-30

Abstract excerpt

Failed T cell-based immunotherapies in the presence of genomic alterations in antigen presentations pathways may be overcome by NK cell-based immunotherapy. This approach may still be limited by the presence of immunosuppressive myeloid populations. Here we demonstrate that NK cells (haNKs) engineered to express a PD-L1 chimeric antigen receptor (CAR) haNKs killed a panel of human and murine head and neck cancer c...

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Literature Corpus work: a284975e-ae1d-59d3-a381-646a629d60ed
DOI: 10.1101/2020.01.30.926535

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