Article

Characterization of B-cell receptor clonality and immunoglobulin gene usage at multiple time points during active SARS-CoV-2 infection

2023-08-09

Abstract excerpt

<h4>Purpose: </h4> Although monoclonal antibodies specific to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are known, information about the B-cell receptor (BCR) repertoire and its change in patients during COVID-19 disease progression is underreported. <h4>Methods: </h4> We used immunoglobulin heavy chain (IGH) variable region (IGHV) spectratyping and next-generation sequencing of peripheral...

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Literature Corpus work: b46b2765-e43b-5700-bd7c-24dee8975717
DOI: 10.22541/au.169156453.35055428/v1

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