Article

Somatic mutations in myeloid transcription factors and in activated signaling genes predict the risk of treatment failure and progression to advanced phase in chronic myeloid leukemia

2023-09-22

Abstract excerpt

<title>Abstract</title> <p>Background Advancements in genomics are transforming the clinical management of chronic myeloid leukemia (CML) towards precision medicine. The impact of epigenetic modifier gene mutations on treatment outcomes is still under debate. Here we studied the association of somatic mutations in the genes of epigenetic modifiers and activated signaling/myeloid transcription factor (AS/MTF), wi...

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Literature Corpus work: a242e101-f9af-5a88-9879-92f183eaf59c
DOI: 10.21203/rs.3.rs-3286758/v1

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