Article

Multiomics and machine learning-based analysis of pseudouridine modifications in pan-cancer

2023-11-25

Abstract excerpt

Pseudouridine widely affects the stability and function of different types of RNA. However, our knowledge of pseudouridine properties in tumors is incomplete. We systematically analyzed pseudouridine synthases (PUSs) expression, genomic aberrations and prognostic features in 10907 samples from 33 tumors. We found that the pseudouridine-associated pathway showed significant abnormalities in tumors and affected pati...

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Literature Corpus work: a2010a5f-de51-563b-994e-17b8432068d2
DOI: 10.21203/rs.3.rs-3562737/v1

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