Article

Optimizing sequential gene expression modulation for cellular reprogramming - Coupled Boolean modeling and Reinforcement Learning based method

2024-03-21

Abstract excerpt

Regenerative medicine entails regenerating damaged cells and tissues from healthy cells through the process of cellular reprogramming. The most common method to achieve reprogramming of cells of one type to another is by modulating the activity of specific genes. However, identifying the most suitable genes for reprogramming is a challenge due to their large number in humans and their complex interactions. This st...

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Literature Corpus work: a1b39d44-9d7b-55f1-b4ab-38b0cd09590d
DOI: 10.1101/2024.03.19.585672

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