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Article

Long non-coding RNA LINC00426 contributes to doxorubicin resistance by sponging miR-4319 in osteosarcoma

3 Jul 2020

Abstract excerpt

BACKGROUND: LINC00426 is a newly identified long non-coding RNA (lncRNA) with unacknowledged biological roles. Here we set out to characterize the expression status of LINC00426 in osteosarcoma and understand its mechanistic involvement in incidence of doxorubicin (Dox) resistance. METHODS: The relative expression of LINC00426 and miR-4319 was determined by real-time PCR. Cell viability and proliferation in...

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PMID: 32620145
DOI: 10.1186/s13062-020-00265-4

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