Article

A strategy to address dissociation-induced compositional and transcriptional bias for single-cell analysis of the human mammary gland

2021-02-11

Abstract excerpt

<h4>Summary</h4> Single-cell transcriptomics provide insights into cellular heterogeneity and lineage dynamics that are key to better understanding normal mammary gland function as well as breast cancer initiation and progression. In contrast to murine tissue, human mammary glands require laborious dissociation protocols to isolate single cells. This leads to unavoidable procedure-induced compositional and transc...

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Literature Corpus work: a19f2ee4-cecc-513a-a2c2-cf8fcc109da0
DOI: 10.1101/2021.02.11.430721

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