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Epithelial and neutrophil interactions and coordinated response to <i>Shigella</i> in a human intestinal enteroid-neutrophil co-culture model

2020-09-04

Abstract excerpt

Polymorphonuclear neutrophils (PMN) are recruited to the gastrointestinal mucosa in response to inflammation, injury, and infection. Herein, we report the development and the characterization of an ex vivo tissue co-culture model consisting of human primary intestinal enteroid monolayers and PMN, and a mechanistic interrogation of PMN-epithelial cell interaction and response to Shigella , a primary cause of chil...

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Literature Corpus work
a18add12-62d0-5e57-90f9-3063ed7dadf5
DOI
10.1101/2020.09.03.281535
Open publication

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Epithelial and neutrophil interactions and coordinated response to <i>Shigella</i> in a human intestinal enteroid-neutrophil co-culture modelDOI 10.1101/2020.09.03.281535
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