Article

Intestinal Enteroid Monolayers Model the Human Intestinal Environment for <i>Escherichia coli</i> Infection

2021-12-21

Abstract excerpt

Enterohemorrhagic Escherichia coli O157:H7 is an enteric pathogen responsible for bloody diarrhea, hemolytic uremic syndrome, and in severe cases even death. The study of O157:H7 is difficult due to the high specificity of the bacteria for the human intestine, along with our lack of sufficiently complex human cell culture models. The recent development of human intestinal enteroids derived from intestinal crypt m...

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Literature Corpus work: 9e8a99c1-95f9-511c-a687-94ab7c369c8b
DOI: 10.1101/2021.12.20.473596

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