Article

The Circadian Clock Controls Hepatic Stellate Cell Activation in Liver Fibrosis via a BMAL1/CK1ε/REV-ERBα/Transgelin Signaling Pathway

2025-09-17

Abstract excerpt

<h4>ABSTRACT</h4> Liver fibrosis is a progressive and life-threatening condition with no effective targeted treatments. Growing evidence indicates a two-way relationship between circadian rhythm and fibrogenesis, although the specific molecular signaling pathways involved are still not well understood. The molecular clock, which governs circadian rhythms, regulates metabolic and cellular functions, and its pharma...

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Literature Corpus work: a17ca53f-9baa-5142-9d74-e20ca12f1fae
DOI: 10.1101/2025.09.12.675813

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