Article
Chapter 4: Protein interactions and disease.
PLoS computational biology - 1 Jan 2012
Gonzalez Mileidy W, Kann Maricel G
Abstract excerpt
Proteins do not function in isolation; it is their interactions with one another and also with other molecules (e.g. DNA, RNA) that mediate metabolic and signaling pathways, cellular processes, and organismal systems. Due to their central role in biological function, protein interactions also control the mechanisms leading to healthy and diseased states in organisms. Diseases are often caused by mutations...
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