Article

Sesamin Exerts Antioxidative Effect by Activating Nrf2 Transcription Factor in Glial Cells of Central Nervous System in Drosophila Larvae

2024-05-21

Abstract excerpt

Sesame seeds are abundant in sesamin, which exerts health-promoting effects such as extending the lifespan of adult Drosophila and suppression of oxidative stress accumulation by activating the Nrf2 transcription factor. Here, we investigated whether sesamin activated Nrf2 in larval tissues and induced the expression of Nrf2 target genes. In sesamin-fed larvae, Nrf2 was activated in the central nervous system (CNS...

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Literature Corpus work: a15b84b6-fb01-5ebb-b1a8-9c52dcc5f9f7
DOI: 10.20944/preprints202405.1335.v1

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